Abstract: The Conradson Carbon Residue(CCR) reaction was carried on the 200 mL Xytel pilot plant by hydrotreatment. According to the experimental results, a kinetic model of first-order and three-lump for the removal of CCR has been proposed based on the structural composition of carbon residue and the mechanism of the removal of CCR. Three-lump reaction kinetic model was compared with one-lump and two-lump models. The result shows that the one-lump reaction kinetic model can't describe the reaction satisfactorily. The predicted error of the two-lump and three-lump reaction kinetic models shows that there is no difference between them when we use the resins and asphaltenes as one lump. When the content of asphaltenes in the residue is low, there is no difference between the results of the two-lump and three-lump models. As we use the three-lump model for the removal of CCR to predict the result, the mean absolute error of the removal of CCR is 0.0056 and the average relative error of the CCR in the product is 1.01％. The three-lump reaction kinetic model can give better precision than the one-lump and the two-lump reaction kinetic models.